Introduction
Underlying pathophysiology is ascending optic atrophy with direct trauma to the inner retina or vasculature, leading to subsequent degeneration and atrophy of axonal tissue.
Thus, it is an ocular event that triggers and leads to optic neuropathy
- May occur within 24 hours and often completes within 7 days
Caused by:
- Retinol photocoagulation (laser treatment)
- Retinitis pigmentosa (and other cone-rod dystrophies) which causes RNFL death and thinning, causing attenuation, optic atrophy, waxy pallor and neuroglial cell death
- CRAO
- Inflammatory conditions like vasculitis
Dead Giveaways
Features:
No prior disc swelling
Waxy pallor
Distinct disc margins
No fibrogliosis
diagnostic features
Clincial Features:
It usually preserves the ONH architecture, but displays a waxy disc pallor with minimal gliotic change.
There may be concurrent retinal vasculature or chorioretinal change.