Sarcoidosis Uveitis

Introduction

Granulomas is the nodular accumulation of immune cells in organs, especially the lungs. As a result, they produce inflammatory molecules (TNF, interferon-gamma, interleukins) which can promote resolution, but also triggers fibrosis.
- Sarcoidosis uveitis manifests in 30-60%
- Anterior uveitis (20-70%) with Koeppe nodules and Busacca nodules
- Can manifest with intermediate uveitis
- Posterior uveitis occurs in 20% of cases

Dead Giveaways

Fundoscopy Features:

In the eye, will present with periphlebitis, perivenous infiltrations/candle wax dripping, choroiditis
Shows the periphlebitis
White sheathing shows the granulomas and candle wax dripping
Shows scarred chorioditis. Pigmentation is from chronicity and scarring

diagnostic features

Secondary Complications:

Cystoid Macular Oedema (CME)
Glaucoma
Cataracts